A arma secreta para nervocure
A arma secreta para nervocure
Blog Article
Patients remain at the heart of the work at Novocure, guiding us forward in our goal to deliver a novel, safe and efficacious cancer therapy that prolongs survival while maintaining patient quality of life.
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TTFields is an innovative treatment modality approved for both newly diagnosed and recurrent GBM in US, Europe and Japan. The mechanism of action has relevance in other cancers. Novocure continues to explore the use of TTFields in a number of cancers of the central nervous system including brain metastases from non-small cell lung cancer (NSCLC) in the ongoing phase III METIS trial.
TTFields therapy uses electric fields to disrupt cell division. TTFields therapy does not stimulate or heat tissue and targets dividing cancer cells of a specific size. TTFields therapy takes advantage of the special characteristics and geometrical shape of dividing cells, which make them susceptible to the effects of the alternating electric fields.
Controle a diabetes. Geralmente, a neuropatia se desenvolve muitos anos depois do diagnóstico da diabetes. 1 Porreiro controle da diabetes pode evitar ou deter esse problema.
Precise placement of the transducer arrays is important to optimize the clinical effect of TTFields. Novocure has developed the NovoTAL software system to optimize array layouts based on individual patient head size, tumour location and magnetic resonance imaging data for the specific characteristics of the patient’s tumour9. Preclinical studies show that the effects of TTFields increase with intensity, which underscores the critical need to understand how TTFields intensities distribute within the tumour region. There are no practical means for measuring field intensities within the brain tissue and tumours of patients undergoing treatment.
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O tempo por início dos efeitos do NERVOCURE pode variar por pessoa para pessoa. Alguns relatos indicam alívio inicial da dor em poucos tempo, enquanto outros mencionam melhora gradual ao longo de várias semanas.
TTFields’ unique mechanism of action underscores key points related to its effective administration and clinical benefit. Unlike chemotherapeutic agents, TTFields are only active while the arrays are affixed to the scalp and the alternating electric fields are generated between the transducer arrays. As a loco-regional and non-invasive targeted therapy, TTFields has the benefit of avoiding systemic adverse events associated with chemotherapy and targeted systemic therapies. The primary treatment-associated adverse event experienced by some patients with TTFields is skin irritation below the arrays, which is predictable and easily manageable in the majority of cases.
Figure 2: Effects of TTFields on replicating cells. TTFields exert directional forces on polar microtubules and interfere with the assembly of the normal mitotic spindle and subsequently trigger mitotic cell death.
We join together with patients, caregivers and advocacy partners in their dedication to redefine living with cancer.
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Tumor Treating Fields have shown a consistent anti-mitotic effect in our preclinical and clinical research spanning more than two decades.